What is Acne?

Acne is an inflammatory condition of the skin that typically occurs on the face and back and is caused by clogged pores. Contributing factors include excess sebum production, hormonal changes, and subsequent invasion of P. acnes bacteria. Sebum is the skin’s naturally occurring oil which in combination with dead skin cells clogs the pores and creates phlegmons, blackheads or closed whiteheads. Inflammation leads to swelling and redness, which appears as the commonly known acne. See more info here

How does ZAPNE work?

ZAPNE has been observed to affect all pathogenic factors causing acne. Its special formulation of ingredients act as antimicrobials and anti-inflammatories, as well as including an active ingredient towelette infused with natural salicylic acid (0.5%), which is an FDA approved acne treatment that helps break down blackheads and whiteheads. It also helps cut down the shedding of the cells lining the hair follicles by encouraging the sloughing (removal) of dead skin cells. Skin is constantly renewing itself by producing new skin cells and shedding old dead ones. The ZAPNE treatment helps keep the pores clear. It also reduces swelling and inflammation of the skin, thereby improving its appearance. However, it is important to avoid direct sunlight for a few days after the treatment. If it is necessary for you to be exposed to direct sunlight, then you should use an effective sunblock.

How does the ZAPNE treatment feel and look?

After applying ZAPNE, you will feel a tingling of the skin as the application dries in about 15 minutes. For a period of about 8 to 24 hours after rinsing (by splashing cold water on the skin, DO NOT SCRUB or use a face wash or soap), you may feel a tingling sensation and your skin may take on a slight redness as if you were in the sun. The tingling and the redness are a result of increased blood flow to the stimulated skin activated by the ingredients and the tiny spicules from the sponge that have assisted in the penetration of the ingredients into the skin. The tingling will subside as the hours pass and then you may notice the skin will feel soft. After a few days you may notice a fine flaking of the old dead skin cells being sloughed-off (peeling), which you can assist by using a wash cloth and gentle circular motions. You should not try another treatment until a full week has passed from the first application of ZAPNE.

Is ZAPNE FDA (Food and Drug Administration) compliant?

ZAPNE is in compliance with the FDA Monograph for Topical Acne Drug Products for Over-the-Counter Use (21 CFR Part 333, Subpart D).

Is ZAPNE tested and proven safe and effective for the treatment of acne?

Observations during therapeutic trials show that ZAPNE can effectively treat and reduce acne development when used topically once a week, usually after two weeks. The natural products used in ZAPNE have been used effectively and safely in Russia and Ukraine for more than 50 years. If used as directed, ZAPNE has been shown to be effective in 95% of those tested in the therapeutic trials according to the doctors who ran the trials. There are no known cases of any problems using ZAPNE.

How is ZAPNE different than other acne treatments?

ZAPNE consists of a natural topical treatment developed to be used on affected areas once a week for 4 weeks, and thereafter weekly as needed. Importantly, it has demonstrated efficacy superior to existing acne treatments without the side effects.

Other acne treatments exhibit a number of adverse effects, which range from mild skin irritation to possible antibiotic resistance and life-threatening issues, such as depression, birth defects and suicides. All existing topical treatments usually require twice daily application and a long-lead time (6-8 weeks) before the benefits of treatment are seen, and in many cases the acne severity actually worsens before it improves. Persons using existing topical treatments often experience skin irritation and dryness, sometimes accompanied by itching and burning. Antibiotics, a mainstay of acne therapy, are becoming less effective as acne bacteria has become more resistant to antibiotic treatments, resulting in ineffective therapy and an increased risk for developing new strains with even stronger antibiotic resistance. Oral retinoids, a form of acne medication, cause birth defects if used by females during pregnancy or before conception. In addition to birth defects, Accutane®, the most effective oral retinoid currently available, has also been linked to depression and suicides.

In comparison with both OTC and prescription treatments, ZAPNE requires less effort by the patient to remain in compliance, has demonstrably greater efficacy based on both pre-clinical studies and therapeutic trials, and carries none of the detrimental side effects of other treatments.

How much does ZAPNE cost?

The online cost for four treatments of Zapne is $69.95.

What is a more detailed definition of acne?

Acne is a multi-factorial disease involving increased sebum production, microbial proliferation, inflammation, and abnormal shedding of hair follicle cells. Acne usually begins around puberty, when hormonal changes increase the activity and size of the sebaceous glands that reside in the pores of the skin. These glands produce an oily substance called sebum to protect the hair follicles and the skin. Increased sebum production and increased shedding of hair follicle cells result in a plug that clogs the hair follicle.

Plugged hair follicles (comedones) are called whiteheads (closed comedones) and blackheads (open comedones). Blackheads are like whiteheads except that the plugged material is in contact with the air, which causes it to darken. The plug creates an environment conducive to the growth of bacteria, such as P. acnes, that naturally live in the skin’s pores. The presence of bacteria releases factors that attract white blood cells that invade the follicle to help clean it. In the process of doing so, the follicle may rupture. When this occurs, swelling or redness can develop around the affected follicle, resulting in the larger bumps or pimples characteristic of acne. These are known as papules and pustules and can sometimes cause scarring. Most persons have both non-inflammatory (whiteheads and blackheads) and inflammatory lesions (papules, pustules and nodules). In mild cases, non-inflammatory lesions predominate. In moderate cases, papules and pustules predominate. Nodular lesions dominate severe acne.

What other factors can contribute to acne?

Other factors that can contribute to acne include age, skin type (dry, oily, or combination), coexisting conditions, lifestyle, menstrual regularity, and premenstrual flare-ups. Birth control pills that contain certain formulation agents (e.g. androgenic progestins) may also provoke acne.

Who suffers from acne?

Acne vulgaris is the most common skin condition encountered by physicians. It is estimated that over 95% of people worldwide suffer from acne at some point in their lives. The number of persons that suffer from acne at any given time in the United States is estimated to be over 17 million. Typically, the disease affects teenagers and young adults between the ages of 12 and 24. In the U.S. alone, over 45 million people have or have had acne, generating demand for prescription strength therapeutics and OTC formulations.

How does one determine the severity of acne?

While there is no single uniform or standardized grading system for measuring the severity of acne, most dermatologists rely on the number and type of lesions present to gauge a patient’s condition.

Are there standard treatments for acne?

Of the 17 million persons in the United States who suffer from acne, approximately 70%, or 12 million persons, either self-medicate using over-the-counter remedies or visit a dermatologist for treatment. Over-the-counter (“OTC”) remedies can be used to treat mild acne cases. Most dermatologists prescribe medication to treat moderate and severe cases where the benefits of treatment are likely to outweigh potentially harmful side effects. In measuring the efficacy outcome of acne treatments, baseline lesion count is typically used.

Is there an ideal treatment for acne?

Most anti-acne agents currently available target only one or two of the four pathogenic factors that contribute to acne. Apart from isotretinoin (first marketed as Accutane by Hoffmann-La Roche), which has severe adverse effects and toxicity, there is no agent that targets multiple pathogenic factors. The ideal agent would target each of the four pathogenic factors that promote acne without producing adverse effects.

Why is it important that ZAPNE is a natural treatment?

Why not, if one can use an all-natural safe treatment to effectively treat acne, then we believe it is a better and safer strategy.

Why does ZAPNE not use benzoyl peroxide?

Although many acne treatments use benzoyl peroxide, ZAPNE believes that its all natural acne treatment is better and does not have the same potential side effects from extended use of benzoyl peroxide, which often causes skin irritation, drying, and according to several studies in Europe causes skin tumors after extended use.

What are the instructions on the ZAPNE box?
  • ZAPNE™ Acne Treatment System
  • Use Only Once a Week
  • Easy 15-minute Mask Treatment
  • Fast Acting
  • Feel and See it Working
  • All Natural Ingredients
  • Four Complete Weekly Treatments

The ZAPNE 2 Part Treatment System consists of Part 1, Medicated Towelette, infused with natural salicylic acid which is applied to the skin first, followed by applying a mask made by mixing Parts 2-A and 2-B. Apply the mask to the skin using your fingers and allow to dry for 15 minutes. Then rinse and let ZAPNE zap your acne.

What are the ingredients of ZAPNE?

Active Ingredients: Salicylic Acid 0.5% from Natural Willow Bark Extract

Indications: For the treatment of Acne

Other Ingredients: Natural Fresh Water Sponge (Spongilla lacustris), Organic Aloe Vera, Natural Sericin, Brown Seaweed, Organic Green Tea, Organic Ginger Root, Willow Bark (Salix alba), Organic Chamomile, Propanediol, Decyl Glucoside, Citric Acid, Potassium Sorbate, Hydrogen Peroxide and Water.